Human genomics is a translational field spanning research, clinical care, public health, and direct-to-consumer testing. However, law differs across these domains on issues including liability, consent, promoting quality of analysis and interpretation, and safeguarding privacy. Genomic activities crossing domains can thus encounter confusion and conflicts among these approaches. This paper suggests how to resolve these conflicts while protecting the rights and interests of individuals sequenced. Translational genomics requires this more translational approach to law.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Handbook of Classical Rhetoric in the Hellenistic Period, 330 B.C.-A.D. 400Terry L. PapillonStanley E. Porter, ed. Handbook of Classical Rhetoric in the Hellenistic Period, 330 B.C.-A.D. 400. Leiden, New York, and Cologne: E. J. Brill, 1997. xvi 1 901 pp. Cloth, Gld. 430, US $253.This massive collection of essays by various authorities will serve as a good basic introduction to the nature and history of classical rhetoric, even (...) for those working outside the Hellenistic period.Its intentions are several: to provide (1) “a comprehensive and wide-ranging introduction to classical rhetoric as it was practiced in the Hellenistic period,” (2) “a thorough introduction to the standard categories of thought, terminology, and theoretical writing on the subject, along with its history and development,” (3) “an assessment of the use of classical rhetorical categories in a representative selection of literary genres and a number of specific writers of the Hellenistic period,” (4) “relevant examples of each term defined and analyzed,” and (5) “areas warranting further research” (xiii–xiv). It has four intended audiences: scholars working with the New Testament, and with Hellenistic classical, and patristic authors. It succeeds in attaining the five stated goals, and will be useful for the four stated audiences. This is especially true for the first audience, New Testament scholars. It will serve a fifth audience well too: it would be a useful book for graduate students, both in classical and in New Testament studies, since it offers clear presentations of issues and future work, points well to other bibliography, and is so broad in scope as to be a concise literary history of classical and biblical literatures.The book is broken into three larger parts. Part I, “Rhetoric Defined,” includes six chapters of introduction to and overview of the five parts of rhetoric. Kennedy’s two chapters (“Historical Survey of Rhetoric” and “The Genres of Rhetoric”) display his typically clear, magisterial, and thorough presentation of the background material. The next four chapters, on the five parts of rhetoric, serve as preparation for the rest of the book. They are of mixed quality. Wuellner’s chapter on arrangement (3), placed before the chapter on invention, is overly difficult, idiosyncratic, and less helpful than it could be, especially when it follows on Kennedy’s clear and controlled prose. Heath’s chapter on invention (4) is a stimulating change of pace. Rather than offering just a straight discussion of the history of invention (though the discussion of its history is thorough), he works through all aspects of the topic with an actual case before him, the response of Antenor during the Trojan War to the Greek request for the return of Helen. He discusses almost every aspect of invention, with thorough reference to the ancient theorists, as he grapples with the actual situation. This provides a good sense of what an orator would actually go through in the composition process. Rowe’s chapter on style (5) follows the four virtues with an emphasis on examples of ornamentation. He begins with the assertion that “at least three reasons account for its [the four virtues’] influence” (121): it provides a “rich nomenclature,” it offers precepts that “apply to any verbal expression,” [End Page 308] not only that used to persuade, and it provides “criteria for judging style that are sufficiently flexible to allow for changing tastes and requirements.”Part II, “Rhetoric in Practice,” treats various genres in ten chapters: the epistle (J. T. Reed), philosophical prose (D. M. Schenkeveld), historical prose (S. Rebenich), poetry and rhetoric (R. Webb), biography (R. A. Burridge), oratory and declamation (D. H. Berry and M. Heath), homily and panegyrical sermon (F. Siegert), the rhetoric of romance (R. F. Hock), apocalyptic and prophetic literature (J. M. Knight), and drama and rhetoric (R. Scodel). These serve as a useful, if uninspiring, survey of several genres in the Hellenistic period, with appropriate reference to important classical antecedents and post-Hellenistic developments. These essays are, in essence, a brief survey of classical and biblical literature. They are thorough and give the appropriate background information with abundant bibliography for further study.Their most useful function is to provide a backdrop for... (shrink)

My purpose in what follows is not so much to defend the basic principle of utilitarianism as to indicate the form of it which seems most promising as a basic moral and political position. I shall take the principle of utility as offering a criterion for two different sorts of evaluation: first, the merits of acts of government, social policies, and social institutions, and secondly, the ultimate moral evaluation of the actions of individuals. I do not take it as implying (...) that the individual should live his life on the basis of constant evaluations of this sort. For there are different levels of decision making each with its appropriate criteria. For example, we each inevitably make many of our decisions from the point of view of our own personal self-fulfilment and this cannot regularly take a directly utilitarian form, nor should the utilitarian want it to do so. His claim is at most that we should sometimes review our life from the point of view of a kind of impersonal moral truth of a universalistic utilitarian character. (shrink)

In this book, T. L. Short corrects widespread misconceptions of Peirce's theory of signs and demonstrates its relevance to contemporary analytic philosophy of language, mind and science. Peirce's theory of mind, naturalistic but nonreductive, bears on debates of Fodor and Millikan, among others. His theory of inquiry avoids foundationalism and subjectivism, while his account of reference anticipated views of Kripke and Putnam. Peirce's realism falls between 'internal' and 'metaphysical' realism and is more satisfactory than either. His pragmatism is not verificationism; (...) rather, it identifies meaning with potential growth of knowledge. Short distinguishes Peirce's mature theory of signs from his better-known but paradoxical early theory. He develops the mature theory systematically on the basis of Peirce's phenomenological categories and concept of final causation. The latter is distinguished from recent and similar views, such as Brandon's, and is shown to be grounded in forms of explanation adopted in modern science. (shrink)

As the editor noted in the last number Freddie Ayer, or Professor Sir Alfred Ayer, played a considerable part in launching the vast enterprise of the Bentham edition. It is fitting, therefore, that something be said in Utilitas about his achievement as a philosopher and the extent to which he falls within the same broad empiricist and utilitarian tradition to which Bentham and J. S. Mill belonged.

The relationship between Bentham's ‘enunciative principle’ and his ‘censorial principle’ is famously problematic. The problem's solution is that each person has an overwhelming interest in living in a community in which they, like others, are liable to punishment for behaviour condemned by the censorial principle either by the institutions of the state or by the tribunal of public opinion. The senses in which Bentham did and did not think everyone selfish are examined, and a less problematic form of psychological hedonism (...) than Bentham's is proposed. (shrink)

Graham Bird’s ‘A Comment on Timothy Sprigge’s Account of William James’, in the last issue of Bradley Studies might have better been called ‘A Comment on Timothy Sprigge’s Account of Graham Bird on William James’ True, that would identify its topic as a somewhat limited one as, if the index is correct, there are just nine sentences on this topic in my book James and Bradley: American Truth and British Reality. But it appears to be the matter which has mainly (...) fired Bird’s article. Bird believes that I have read his own book, William James, carelessly and misrepresent what he said, claiming to illustrate this with copious quotations from his own book. He dismisses ‘the unworthy thought that one who treats my [Bird’s] text so carelessly might not be a very reliable guide to James’s’. My own view is that ‘unworthy thoughts’ are better not expressed and I shall keep quiet about any of mine which might be deemed such. I don’t think that I read either Bird or James himself carelessly. If I was at all misleading, by failing to emphasise that Bird’s position was that James was attempting to unite the cognitive and the affective, I apologize; the offending remark was my response to his presupposing throughout his commentary the prima facie relevance of this distinction to the interpretation of James’s pragmatism. As for my not having read James carefully, his work has been my favourite philosophical reading for more than forty years, and I have puzzled endlessly over parts of it which I found problematic. I read Bird’s book thoroughly when I reviewed it, and my copy of it is covered in detailed pencil comments. (shrink)

This series will include monographs and collections of studies devoted to the investigation and exploration of knowledge, information, and data-processing systems of all kinds, no matter whether human, (other) animal, or machine. Its scope is intended to span the full range of interests from classical problems in the philosophy of mind and philosophical psychology through issues in cognitive psychology and sociobiology (concerning the mental capabilities of other species) to ideas related to artificial intelligence and computer science. While primary emphasis will (...) be placed upon theoretical, conceptual, and epistemological aspects of these problems and domains, empirical, experimental, and methodological studies will also appear from time to time. While most philosophers and psychologists tend to believe that the rise of cognitive psychology has occurred concomitant with the decline of operant psychology, Terry L. Smith contends that nothing could be further from the truth. He maintains that operant psychology has discovered (and continues to discover) reasonably well-confirmed causal principles of intentional behavior, which go beyond what cognitive psychology can provide, while cognitive psychology, in tum, has the potential to supply analyses (and explanations) that account for them. Smith thus advances a surprising but nonetheless illuminating perspective for appreciating the place of operant conditioning within the discipline of psychology in this rich and fascinating work. J. H. F. (shrink)

This paper falls into two main parts. In the first I shall review some of the things Bradley said about Christianity as he conceived it. In the second I shall use this review to spell out more formally the logical relations between some main doctrines of Christianity and Bradley’s mature philosophy.

This chapter begins with an account of the life of Spinoza. It then discusses his great work, the Ethics, and the proof of its fundamental claim that there is just one substance, and that everything else which in any manner exists is a mode of it. There follows an account of Spinoza’s form of determinism and its ethical and religious significance and of his distinction between rational and irrational action. Finally there is a discussion of Spinoza’s views on institutionalized religion, (...) and on Jesus. The chapter ends by asking whether Spinozism offers a ‘personal religion’. (shrink)

Graham Bird’s ‘A Comment on Timothy Sprigge’s Account of William James’, in the last issue of Bradley Studies might have better been called ‘A Comment on Timothy Sprigge’s Account of Graham Bird on William James’ True, that would identify its topic as a somewhat limited one as, if the index is correct, there are just nine sentences on this topic in my book James and Bradley: American Truth and British Reality. But it appears to be the matter which has mainly (...) fired Bird’s article. Bird believes that I have read his own book, William James, carelessly and misrepresent what he said, claiming to illustrate this with copious quotations from his own book. He dismisses ‘the unworthy thought that one who treats my [Bird’s] text so carelessly might not be a very reliable guide to James’s’. My own view is that ‘unworthy thoughts’ are better not expressed and I shall keep quiet about any of mine which might be deemed such. I don’t think that I read either Bird or James himself carelessly. If I was at all misleading, by failing to emphasise that Bird’s position was that James was attempting to unite the cognitive and the affective, I apologize; the offending remark was my response to his presupposing throughout his commentary the prima facie relevance of this distinction to the interpretation of James’s pragmatism. As for my not having read James carefully, his work has been my favourite philosophical reading for more than forty years, and I have puzzled endlessly over parts of it which I found problematic. I read Bird’s book thoroughly when I reviewed it, and my copy of it is covered in detailed pencil comments. (shrink)

Empiricism in philosophy is either a method or a theory. The two are separable: one might hold that all knowledge is empirical but that philosophy does something other than add to our knowledge, e.g., that it clarifies concepts; or one might hold that philosophy’s method is empirical and that one of the things known in that way is that not all knowledge is empirical, e.g., mathematics. And what is the empirical? If it is knowledge based on observation, then what is (...) it that can be observed? If philosophy is in method empirical, the range of the observable must be broad, perhaps including mental processes, human history, social institutions such as language, and even the difference between good and evil.In Peirce’s... (shrink)

Peirce persistently proclaimed both idealism and realism, terms that in philosophy's history have had varied meanings, in some of which they designate opposed doctrines; his use of them also varied in meaning. The aim of Robert Lane's important new book is to trace the evolution of Peirce's idealism and realism and to show that, in the end, whatever misadventures occur en route, these doctrines, in Peirce's version of them, are not opposed. Lane explores connections to other Peircean topics: truth, pragmatism, (...) modality, generality, vagueness, continuity. However, he retains his focus, which enables him to examine Peirce's idealism and realism with extraordinary care and thoroughness.Lane's method is, in the first... (shrink)

This classic study of Santayana was the first book to appear in the _Arguments of the Philosophers_ series. Growing interest in the work of this important American philosopher has prompted this new edition of the book complete with a new preface by the author reassessing his own ideas about Santayana and reflecting the new interest in the philosopher's work. A select bibliography of works published about Santayana since the book's first appearance is also included.

In 1952, the Diagnostic and Statistical Manual of Mental Disorders (DSM) system of creating, validating, studying and employing a diagnostic system in clinical psychiatric practice was introduced. There have been several updates and revisions to this manual and, regardless of its a theoretical framework, it actually does have a framework and presupposition. Essentially the DSM dictates that all psychiatric disorders are syndromes, or a collection of symptoms that commonly occur together and impair psychosocial functioning. These syndromes allow for homogenous groups (...) of patients to be studied and psychotherapies and pharmacotherapies to be developed. This editorial will examine the DSM system with regards to its applicability to central nervous system dysfunction where psychiatric disorders are concerned. Specifically, the brain does not follow categorical, or syndromal, constructs. In fact, the psychiatric patient likely inherits several risk genes that promote abnormal proteins along several neuropathways in the brain. These abnormalities create dysfunctional neurocircuits which create individual psychiatric symptoms, but not a categorical syndrome or diagnosis. The concept that the DSM may be excellent for clinical diagnostic purposes, but less correct in its assumptions for a psychopharmacologist's treatment approaches will be discussed. (shrink)

This passage has caused much discussion and much variety of opinion, and it still remains doubtful whether the later commentators in their efforts at exact interpretation have been more successful than the earlier ones. The general sense is sufficiently clear. Medea is making an apology to the Chorus of sympathizing Corinthian ladies for her delay in appearing before them. So far all are agreed. The difficulties, real or unreal, arise when we begin to inquire what form the apology actually takes. (...) First of all there are doubts as to the meaning of το ς μ μᾂπο. in the Scholia. we have a gloss μῂ όρώμνο είνα. and the explanation το Xωρίςεσθα καì ᾂτν ποθεν μμάτων είνα. Many scholars have taken exception to this view on two grounds, as stated by Verrall ad loc, because ‘the sense of motion is not there, and there is no reference to any eyes in particular.’ He requires either authority or analogy for this. As far as the absence of motion is concerned, it is sufficient to refer to Thuc. 1, 7 αί δ παλααί ᾀπθαλσσης μλλον ῲκίσθησαν id I, 99ναμῄ ᾀπ οκου σ,γ. Il. B 292 μένεν ᾀπ ᾑς ᾀλòΧοο. Then there is the analogous expression αί γàρ δῂ μοᾀπ οὒατος ώδε γένοτο . As to the second objection, why is it necessary that the eyes of anyone in particular should be referred to ? There is no more ambiguity here than there is in Il Ψ 53 θâσσον ᾀπ θαλμν, where the meaning is ‘so as to be out of sight, not of me or you, but of everybody.’ In fact, it could not be maintained with any show of reason that ᾀπθαλμνand ᾀποὒατς could not mean ‘out of sight’ and ‘out of hearing’. (shrink)

Ranging from Joseph Bellamy to Hilary Putnam, and from early New England Divinity Schools to contemporary university philosophy departments, historian Bruce Kuklick recounts the story of the growth of philosophical thinking in the United States. Readers will explore the thought of early American philosphers such as Jonathan Edwards and John Witherspoon and will see how the political ideas of Benjamin Franklin, Thomas Paine and Thomas Jefferson influenced philosophy in colonial America. Kuklick discusses The Transcendental Club (members Henry David Thoreau, Ralph (...) Waldo Emerson) and describes the rise of pragmatism centered on Metaphysical Club of Cambridge (and members William James, Oliver Wendell Holmes, and Charles Peirce). He examines the profound impact Darwinism had on American philosophy and looks at Idealists such as the Kantian Josiah Royce and the Hegelian John Dewey. The book shows how, in the twentieth century, the Nazi conquest of Europe unleashed a flood of European intellectuals onto these shores, including such major thinkers as Theodore Adorno, Erich Fromm, Rudolph Carnap, and Alfred Tarski. Finally, Kuklick examines the contributions of such contemporary philosophers as Sidney Hook and Willard Quine and such books as John Rawl's A Theory of Justice and Herbert Marcuse's One Dimensional Man. Kuklick pulls no punches in portraying the state of American philosophy today and its contested role in the intellectual life of the nation and the world. The range of philosophical thought in our nation's history has been great, from Edwards's Religious Affections to Kuhn's The Structure of Scientific Revolutions, and Bruce Kuklick has captured it all in a book that blends intricate details with sweeping vision. (shrink)

This introductory chapter starts the discussion by some general remarks on what makes a belief system a religious one and the criteria for calling something ‘God’. There is a brief discussion of Descartes and of Pascal and the relation between the expressions ‘the Absolute’ and ‘God’ is briefly considered.